Research Interests
Check Out Our Virtual LAB TOUR!
Check out the New and Improved Genome Database for Rosaceae (GDR) Website!
GDR
is a curated and integrated web-based relational database. GDR contains:
- Comprehensive data of the genetically anchored peach physical map, annotated EST databases, maps and markers and all publicly available Rosaceae sequences.
- Annotations of ESTs include contig assembly, putative function, SSRs, ORFs, Gene Ontology and anchored position to the peach physical map where applicable. Our integrated map viewer provides graphical interface to the genetic, transcriptome and physical mapping information.
- CMap, to view comparisons of genetic and physical maps. ESTs, BACs and markers searches where the search result sites are linked to the integrated map viewer or to the WebFPC physical map sites. Assemble them with the CAP3 Server or search sequences for microsatellites using the SSR server.
- Query a comparison of sequences with the annotated GDR sequences via a dedicated sequence similarity server running either the BLAST or FASTA algorithm.
The Powdery Mildew King! See what Derick's up to!
Powdery Mildew is a major pathogen of concern for Rosaceae species in the Pacific Northwest. We have been successful in identifying a resistance gene which has the potential to confer a broad spectrum resistance to powdery
mildew. we are currently carrying out comparative and functional genomics
regarding this resistance gene. Keep checking back for more news!
Plus! Pictures from our trip to Chile for the 4th Rosaceae Genomics Conference!
Check out our collaborative work on the Functional Domains in Plants!
- Construct/overlay chromosomal maps of replication origins through the use of powerful microarray technologies with immunological tools and CHiP analysis and/or selective labelling techniques.
- Generation of origin maps for the the whole Arabidopsis chromosome 4, and the short arm of chromosome 1, and maps for matrix binding affinity, transcription, methylation and histone modification.
About Dr. Main's lab: We are currently working on improvement of a www accessible Genome Database for Rosacaeae (GDR) as a resource for the Rosaceae community; development of protocols and computational pipelines for processing, analysis, and visualization of genomic and cDNA sequences; development of algorithms to determine unigenes from expressed sequence tags datasets; and development of www accessible sequence processing resources for smaller scale genomics laboratories and researchers. Other research includes microarray gene expression data management, analysis and visualization tools. So come on in!